Anthocyanins are water-soluble naturally occurring pigments that are therapeutically beneficial and that have gained considerable interests by researchers in the field of phytopharmaceuticals and pharmacology. The evidence based scientific reports on the potential and efficacy of anthocyanins has caused an upsurge in their testing in clinical trials and formulation of herbal drug supplements since the past few decades. Their structural attributes enable them to be absorbed and react with various biomolecules in the human body, to provide beneficial physiological benefits. The anthocyanins are 2-phenylbenzopyrylium derivatives of dietary phenolics and exhibit antioxidant, anti-inflammatory and protective effects against metabolic and cardiovascular conditions. The metabolism of anthocyanins and their stability in-vivo in human body and during post-harvest storage still needs extensive investigation to fully explore their benefits. In the present chapter, we discuss the chemistry, medicinal uses in folklore/traditional medicine and the natural sources of their occurrence. The pre-clinical, clinical and pharmaceutical applications are also discussed, to emphasize the consumer demands and medicinal value of anthocyanins.
Part of the book: Flavonoids
Lactic acid bacteria are gram-positive microorganisms that are characterized by the production of lactic acid as a key fermentation product. LAB, specifically Lactobacillus delbrueckii subsp. bulgaricus, are essential dairy starter cultures for the manufacture of several fermented dairy products such as yogurt. Some LAB are useful microorganisms and are well known to have probiotic effects to provide foods with unique sensory qualities such as aroma and taste. Probiotic strains help to strengthen the human immune system, increasing the body’s resistance to diseases. Additionally, probiotics and postbiotics improve gut microbiome balance and prevent health issues. Postbiotics are substances that are produced by microbes’ metabolic activities and have a positive impact on diseases, either directly or indirectly. Extensive research has shown that postbiotics possess immunomodulatory and significant clinical effects. Their use has been found to enhance general health and alleviate symptoms of various disorders in healthy individuals. Furthermore, postbiotics exhibit anti-inflammatory, antioxidant, and anticancer properties. Therefore, this chapter presents an overview and the importance of LAB as a probiotic and its importance to human health, metabolic fermentation, and antioxidant potential. The review also discusses different biotechnological methods that improve the survival rate of probiotics during processing and GIT transit like microbial encapsulation.
Part of the book: Current Issues and Advances in the Dairy Industry